NETS - Medicinal Chemistry & Biological Development

What are medicinal chemistry and biological development and why are they important in drug development?

Medicinal chemistry is the design and synthesis of chemical compounds intended to be used as medicine in humans. Using medicinal chemistry, compounds that are initially identified as having potential therapeutic effects can be optimized to reduce unwanted side effects and improve their interaction with the therapeutic target.

Biological development refers to conducting similar processes for biologics, which are produced differently than traditional drug compounds. Biologics are typically produced by inserting DNA into a living cell, which that cell then converts into a desired protein. Following production, biologics may need to modified to ensure that they function as desired in more complex organisms. Specific modifications to biologics ensure that they are sent to the correct places within an organism's body, or prevent undesired interactions.

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