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NETS - Therapeutic & Clinical Endpoints

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What are therapeutic & clinical endpoints and why are they important in drug development?

A clinical and therapeutic endpoint refers to the occurrence of an outcome (that is, a sign or a symptom) that constitutes one of the targets of the trial. They are distinct measurements of disease characteristics that reflect the effect of a therapeutic intervention, in terms of how recipients of a drug or therapy feel, function, or survive. These endpoints may also signal a point at which a participant should withdraw from a trial or study.

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